First in…

Since 1988, we have achieved a number of “firsts” in Bulgaria such as first test tube baby born (1988)

1996

First ICSI in Bulgaria

1998

First PESA in Bulgaria

2000

First application of the FISH technique in Bulgaria
First polar body biopsy in Bulgaria
First successful application of Assisted hatching in Bulgaria

2003

First successful pregnancy with frozen embryos through vitrification in Bulgaria
First successful fertilization of oocytes with immature spermatozoa in Bulgaria

2004

First successful pregnancy with frozen spermatozoa, retrieved with PESA in Bulgaria
First successful in vitro maturation of immature oocytes in Bulgaria in Bulgaria

2005

First successful egg freezing and ovarian tissue cryopreservation in Bulgaria in Bulgaria

2006

First successful co-cultivation of embryos with endometrial cells in Bulgaria in Bulgaria

2007

First successful fertilization of cryopreserved and thawed human oocytes by ICSI in Bulgaria
First clinical application of local immunomodulation with peripheral monocytes in Bulgaria
First baby born with co-cultivation of the embryo with endometrial cells in Bulgaria

2008

First twin birth following vitrification in Bulgaria

2010

First use of the MACS selection method to eliminate DNA fragmented spermatozoa in Bulgaria
First CASA – SCASA system in Bulgaria

2011

First case of PGD for single gene disorders and HLA typing in Bulgaria was performed in our center in in Bulgaria
First 24/7 real time embryo monitoring system in Bulgaria

2012

First successful endometrial scrach in Bulgaria

2013

First successful MSOME and IMSI in Bulgaria
First introduce EmbryoScope – a time-lapse imaging in Bulgaria